Gut Irritation and Inflammation It is generally recognised that inflammation of the intestinal wall is caused by a variety of factors, including certain foods and medications, chemical toxins, incompletely digested food proteins, and infectious microorganisms in the intestinal tract. Gluten, lactose and milk protein can contribute to gut inflammation, as can those foods that a person may be allergic to. Medications such as antibiotics, steroids, aspirin, and nonsteroidal anti-inflammatory drugs can irritate the intestinal wall and cause the overgrowth of certain microbes such as yeasts, which in turn cause further irritation to the gut membrane. In fact, many people feel their problems first began after the administration of multipleprescriptions of antibiotics. Chemicals ingested in foods, such as artificial additives and preservatives, food dyes, certain sweeteners, artificial flavouring agents, pesticides, and hormones, can contribute to the toxic burden on the digestive system and cause oxidative damage within the gut. Further problems can occur when there is an overgrowth of yeast, bacteria, parasites, or other organisms. The resulting inflammation of the intestinal wall usually leads to an overly permeable ("leaky") gut membrane, which can be the origin of many of the systemic complaints seen in chronique fatigue an other long term health problems.